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Lysosomal Google Alerts
by deirdra , 4 pages, 0 comment. Public.
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    UI Scientists Use Blood Brain Barrier as Therapy Delivery System

    The Gazette

    By
    Aaron Hepker


    Story Created:
    Sep 26, 2009 at 3:49 PM CDT

    Story Updated:
    Sep 26, 2009 at 3:49 PM CDT

    IOWA CITY — University of Iowa researchers have discovered a way to turn blood vessels surrounding brain cells into a production and therapy delivery system.

    The blood brain barrier is generally considered an obstacle to delivering therapies from the bloodstream to the brain.

    Working with animals of a group of fatal neurological disorders called lysosomal storage diseases, the UI team found the diseases cause unique and disease-specific alterations to the blood vessels of the blood brain barrier.
    http://www.kcrg.com/news/local/61913077.html
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  2.    News Sections Home Local Villages Sports Lifestyles Obituaries Advertising Automotive Classifieds Place An Ad Service
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    Times Yellow Pages Waterfront Inn Daily Sun About Us Awards Contact Us Subscribe Special Publications Magazine Cover Magazine Feature 1 Magazine Feature 2 Recreation News Activities Schedules Current Weather      News Submitted photo
    Albert Einstein College of Medicine associate professor Dr. Ana Maria Cuervo, center, believes protein degradation within cells leads to aging. Cuervo, an expert in the field of protein degradation and of the biology of aging, is flanked by fourth-year graduate students Urmi Bandyopadhyay, left, and Maria Kon. Age-old questions



    Tuesday, September 29, 2009 7:28 AM EDT

    Researchers strive to unravel mysteries of aging process

    By GARY CORSAIR, DAILY SUN

    THE VILLAGES — While you golf, play pickleball and line dance, scientists are working to give you more tee times, more serves and more boot scootin’.

    At the Albert Einstein College of Medicine, Dr. Ana Maria Cuervo is studying how proteins are transported.

    Researcher David Sinclair is manipulating cells at Harvard Medical School.

    At the University of Sydney School of Medicine, Gustavo Duque is analyzing the effect of Vitamin D on bone and muscle mass.



    All three researchers — and dozens of others — are involved in a quest to slow, or halt, the aging process in humans. And, believe it or not, one or more of them may reach that goal in your lifetime.

    Scientists already know how we age: Cells deteriorate and DNA changes; therefore, we become more prone to disease and eventually waste away. Now, researchers are fixated on determining why organs and systems slow and stop functioning.

    Cuervo and others involved in gerontology (the study of aging) believe they are on the threshold of solving the mystery of why we grow old.
    http://www.thevillagesdailysun.com/articles/2009/09/29/news/news01.txt
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  3. About the Foundation About SENS Our Research Help Us Events Donate Welcome Mission Statement Who's Who... Founders Interim Board A Brief History Introduction Overview... SENS and Aging SENS: An Engineering Solution Repairing Damage... 7 Deadly Things AmyloSENS ApoptoSENS GlycoSENS LysoSENS MitoSENS OncoSENS RepleniSENS Delivery Publications FAQ: SENS and Aging... Status and Progress Challenging Questions Timeframe Wider Concerns Introduction Research Center... Introduction Who's Who Research... Atherosclerosis Immunosenescence Macular Degeneration Portfolio How You Can Help... Donate Work for the Research Center Extra-mural Initiatives... Principal Investigators Graduate and Postdoctoral Researchers Academic Initiative... Introduction Who's Who Enrollment... How to Enroll Standard Enrollment Checklist Advanced Enrollment Checklist Standard Application Advanced Application Student Leadership Program Volunteer SLP Application Volunteer Application
    http://www.sens.org/index.php?pagename=lysosens
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  4. skip to main | skip to sidebar Next Big Future

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    September 04, 2009

    SENS4 : Antiaging conference coverage

    Ouroboros has coverage of the SENS4: Antiaging conference.

    The SENS site has all of the conference abstracts

    UPDATE: SENS4, Session 6: Eliminating recalcitrant intracellular molecules: other



    Claude Wischik spoke about preventing aggregation of tau protein, which is implicated in Alzheimer’s disease. Clinical trials of their aggregation-inhibiting drug Rember are promising.

    Andrei Seluanov talked about naked mole rats, those odd-looking miracle rodents that live for 30 years and don’t seem to ever get cancer. Mole rat contact inhibition/cancer resistance was controlled by p53 and pRB, both known tumour suppressors.

    Alex Whitworth spoke about the relationship between mitochondrial degradation and Parkinson’s disease genes [Parkin and PINK1 genes].














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    http://nextbigfuture.com/2009/09/sens4-antiaging-conference-coverage.html
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